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    Sterilization

    Validated process used to render a device free from viable microorganisms.

    Reviewed by Christian Espinosa, Founder, Blue Goat CyberLast reviewed May 5, 2026

    Definition

    Sterilization is a validated process used to render a product free from viable microorganisms. Common modalities include ethylene oxide (EO), gamma radiation, electron beam, and steam.

    What this means in practice

    FDA has prioritized reducing EO use due to environmental concerns, accelerating adoption of alternative modalities under ISO 11135 and related standards.

    Mentioned in recent activity

    5 entries

    Primary references

    3 sources
    Link health: 2 verified 1 bot-blocked· last checked 2026-05-09
    FDA·1ISO·1IMDRF/GHTF·1
    1. 1
      FDA Sterilization
      Bot-blocked
      FDAfda.gov
    2. 2
      ISO 13485 Standard Page
      Verified
      ISOiso.org
    3. 3
      GHTF/IMDRF Process Validation Guidance
      Verified
      IMDRF/GHTFimdrf.org

    Inline markers like [1] jump to the matching reference above.