All terms
Incremental Cost-Effectiveness Ratio
Cost per additional unit of health outcome (often QALY) versus comparator.
Reviewed by Christian Espinosa, Founder, Blue Goat CyberLast reviewed May 5, 2026
Definition
ICER = (Cost_new − Cost_comparator) / (Effect_new − Effect_comparator). A foundational HTA metric. The U.S. organization ICER (Institute for Clinical and Economic Review) produces influential value assessments.What this means in practice
Often confused with the U.S. organization of the same name. Manufacturers must distinguish between the math and the organization in commercial conversations.Primary references
3 sourcesLink health: 2 verified 1 needs review· last checked 2026-05-09
ICER·1AdvaMed·1CMS·1
- 1
ICER (US)VerifiedICERicer.org
- 2
AdvaMed - Payment & CoverageVerifiedAdvaMedadvamed.org
- 3
CMS - CoverageNeeds reviewCMScms.gov
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