CybersecurityConnected & Cyber-Physical DevicesH-ISAC

Health Information Sharing and Analysis Center

Member-driven nonprofit that operates the trusted sharing community for cyber and physical threat intelligence across the healthcare sector.

Reviewed by Christian Espinosa, Founder, Blue Goat CyberLast reviewed June 20, 2026

Definition

Health-ISAC (Health Information Sharing and Analysis Center) is a global, nonprofit, member-driven organization that serves as the trusted threat intelligence sharing community for healthcare and public health (HPH) sector members, hospitals, payers, pharmaceutical manufacturers, biotech, and medical device manufacturers. H-ISAC operates a Threat Operations Center (TOC), runs the Medical Device Security Information Sharing Council (MDSISC), publishes the Annual Threat Report, hosts a Member Exchange of indicators of compromise (IoCs) in STIX/TAXII, and coordinates incident response across members during active campaigns.

What the regulation says

FDA's premarket and post-market cybersecurity guidance encourages manufacturers to participate in Information Sharing and Analysis Organizations (ISAOs), H-ISAC is the recognized ISAO for the HPH sector and is referenced in the HSCC Joint Security Plan.

What this means in practice

For medical device manufacturers, H-ISAC membership and MDSISC participation are increasingly expected, both by hospital customers (who want their vendors plugged into sector intel) and by FDA, which references 'participation in an ISAO' as evidence of a mature post-market cybersecurity program. The Medical Device Vulnerability Information Sharing initiative coordinates coordinated vulnerability disclosure across the membership.

Common pitfalls

•Joining for branding rather than operationally consuming and contributing intel, the value is in the bidirectional flow.
•Confusing H-ISAC with HSCC, HSCC is the Health Sector Coordinating Council (policy/standards), H-ISAC is operational threat sharing.
•Assuming H-ISAC replaces internal CVD, coordinated disclosure with H-ISAC accelerates sector-wide notification but doesn't substitute for your own program.

Primary references

3 sources

Link health: 3 verified· last checked 2026-06-20

Health-ISAC·1MDCG·1HSCC·1

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