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    Quality & RiskQuality System

    Complaint Handling

    Process for receiving, evaluating, and responding to device complaints.

    Reviewed by Christian Espinosa, Founder, Blue Goat CyberLast reviewed May 5, 2026

    Definition

    Per 21 CFR 820.198, manufacturers must maintain procedures for receiving, reviewing, and evaluating complaints, with timely investigation and - when reportable - submission to FDA under 21 CFR Part 803.

    What this means in practice

    Complaint handling is the entry point for the post-market feedback loop, feeding CAPA, vigilance, and risk management updates.

    Cross-references

    Precedes

    Comes before in a typical workflow or lifecycle.

    Primary references

    3 sources
    Link health: 2 verified 1 needs review· last checked 2026-05-09
    eCFR·1MDIC·1FDA·1
    1. 1
      21 CFR 820.198
      Needs review
      eCFRecfr.gov
    2. 2
      MDIC Case for Quality
      Verified
      MDICmdic.org
    3. 3
      FDA - Quality Systems
      Verified
      FDAfda.gov

    Inline markers like [1] jump to the matching reference above.