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    Bottom-Up Market Sizing

    Building market size from procedure volumes × price × penetration.

    Reviewed by Christian Espinosa, Founder, Blue Goat CyberLast reviewed May 5, 2026

    Definition

    Bottom-up sizing builds TAM from defensible inputs - incidence/prevalence, procedure volumes, addressable subset, average selling price, and realistic penetration curves - rather than top-down market percentages.

    What this means in practice

    Preferred by sophisticated MedTech investors. Inputs are sourced from registries (NCDR, STS), claims (HCUP, Medicare 5%/100%), and society reports.

    Primary references

    3 sources
    Link health: 2 verified 1 needs review· last checked 2026-05-09
    AHRQ HCUP·1AdvaMed·1MedTech Europe·1
    1. 1
      HCUP
      Verified
      AHRQ HCUPhcup-us.ahrq.gov
    2. 2
      AdvaMed Code of Ethics
      Verified
      AdvaMedadvamed.org
    3. 3
      MedTech Europe Code of Ethical Business Practice
      Needs review
      MedTech Europemedtecheurope.org

    Inline markers like [1] jump to the matching reference above.