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Software & AISoftware Lifecycle
Interoperability
Ability of devices and systems to exchange and use information.
Reviewed by Christian Espinosa, Founder, Blue Goat CyberLast reviewed May 5, 2026
Definition
Interoperability is the ability of two or more medical devices, products, technologies, or systems to exchange and use information with consideration for safety, effectiveness, and security.What this means in practice
FDA's interoperability guidance recommends defining the purpose of an electronic interface, anticipated users, risk management, validation, and labeling.Primary references
3 sourcesLink health: 3 verified· last checked 2026-05-09
- 1
FDA Interoperability GuidanceVerifiedFDAfda.gov
- 2
FDA - Software as a Medical Device (SaMD)VerifiedFDAfda.gov
- 3
FDA - AI/ML-Enabled Medical DevicesVerifiedFDAfda.gov
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