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Blinding and Masking

Procedures that hide treatment assignment from patients, investigators, or assessors to reduce bias.

Reviewed by Christian Espinosa, Founder, Blue Goat CyberLast reviewed May 5, 2026

Definition

Single-, double-, and triple-blinding apply progressively to patients, investigators, and outcome assessors. Device trials often achieve only assessor-blinding due to the visible nature of devices/procedures.

What this means in practice

Independent core labs and blinded adjudication committees are standard mitigations for device trials where full blinding is impossible.

Primary references

3 sources

Link health: 3 verified· last checked 2026-05-09

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On this term

Category: Clinical & Trials
Sources: 3
Updated: 5/5/2026

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Procedures that hide treatment assignment from patients, investigators, or assessors to reduce bias.

·Independent core labs and blinded adjudication committees are standard mitigations for device trials where full blinding is impossible.
·Device trials often achieve only assessor-blinding due to the visible nature of devices/procedures.

Remember this

Procedures that hide treatment assignment from patients, investigators, or assessors to reduce bias.

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