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Reimbursement [Hospital Buyer & Reimbursement](/ecosystems/hospital-buyer)APC 

# Ambulatory Payment Classification

The Medicare grouping system that determines hospital outpatient payment amounts under OPPS, analogous to MS-DRGs for inpatient.

Reviewed by [Christian Espinosa, Founder, Blue Goat Cyber](/authors/christian-espinosa) Last reviewed May 9, 2026 

## Definition

Ambulatory Payment Classifications (APCs) are the unit of payment under the Medicare Hospital  [Outpatient Prospective Payment System](/terms/opps) (OPPS), established by the Balanced Budget Act of 1997 and effective August 2000. CMS groups outpatient procedures with similar clinical characteristics and resource use into APCs and pays a single bundled amount per APC, with status indicators that determine whether the service is separately payable, packaged into another APC, or excluded. 

What the regulation says

[OPPS](/terms/opps) rules are issued annually in the OPPS Final Rule (calendar-year cycle). 42 CFR 419 governs the system. CMS publishes the APC list and status indicators in OPPS Addendum B. 

## What this means in practice

APC assignment plus pass-through status ( [TPT](/terms/tpt)) determines the outpatient economics of a new device. Many MedTech launch strategies hinge on securing a favorable APC and, where eligible, transitional pass-through payment. 

Common pitfalls

-   • Assuming an inpatient NTAP equivalent exists in OPPS, it does not; the outpatient analog is TPT. 
-   • Missing the annual OPPS comment window (June-September) for APC reassignment requests. 

## Related terms

Grouped by theme 

### Editor's picks

· Hand-selected related concepts 

[

Reimbursement

Inpatient Prospective Payment System(IPPS) 

Medicare's payment system for inpatient hospital stays.





](/terms/ipps)[

Reimbursement

MS-DRG(MS-DRG) 

Medicare's inpatient hospital payment classification system.





](/terms/ms-drg)[

Reimbursement

New Technology Add-On Payment(NTAP) 

Supplemental Medicare payment for inpatient use of qualifying new technologies.





](/terms/ntap)[

Reimbursement

Outpatient Prospective Payment System(OPPS) 

Medicare's payment system for hospital outpatient services.





](/terms/opps)

### More in Reimbursement

· Same category 

[

Reimbursement

Transitional Pass-Through Payment(TPT) 

Supplemental outpatient payment for new device technologies.





](/terms/tpt)[

Reimbursement

340B Drug Pricing Program(340B) 

Federal program providing discounted drugs to safety-net providers.





](/terms/340b)[

Reimbursement

ASC Site-of-Service Shift

Migration of procedures from hospitals to ambulatory surgery centers.





](/terms/asc-shift)[

Reimbursement

Budget Impact Model(BIM) 

Financial model that estimates the total cost consequences of adopting a new technology to a payer's budget over a defined horizon.





](/terms/budget-impact-model)

Cited by

Where this term appears across MedTech Terms.

Ecosystems (1)

-   [Hospital Buyer & Reimbursement](/ecosystems/hospital-buyer)

## Primary references

3 sources 

Link health:  3 verified · last checked 2026-06-20 

CMS· 1 eCFR· 1 AMA· 1 

1.  [1 
    
    CMS, Hospital OPPS
    
    Verified 
    
    CMS · cms.gov 
    
    
    
    ](https://www.cms.gov/medicare/payment/prospective-payment-systems/hospital-outpatient)
2.  [2 
    
    42 CFR 419
    
    Verified 
    
    eCFR · ecfr.gov 
    
    
    
    ](https://www.ecfr.gov/current/title-42/chapter-IV/subchapter-B/part-419)
3.  [3 
    
    AMA CPT Resources
    
    Verified 
    
    AMA · ama-assn.org 
    
    
    
    ](https://www.ama-assn.org/practice-management/cpt)

Inline markers like \[1\]  jump to the matching reference above.

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MedTech Terms is a community resource sponsored by [Blue Goat Cyber](https://bluegoatcyber.com). Definitions are independent of any vendor.

On this term

Category

Reimbursement

Acronym

APC

Sources

3

Updated

5/9/2026

[Compare with another term](/compare?a=apc)

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Card Lesson Quiz

The Medicare grouping system that determines hospital outpatient payment amounts under OPPS, analogous to MS-DRGs for inpatient.

-   · APC assignment plus pass-through status (TPT) determines the outpatient economics of a new device. 
-   · Many MedTech launch strategies hinge on securing a favorable APC and, where eligible, transitional pass-through payment. 

Remember this

Watch out: Assuming an inpatient NTAP equivalent exists in OPPS, it does not; the outpatient analog is TPT.

Related terms

-   [Outpatient Prospective Payment System(OPPS) ](/terms/opps)
-   [Transitional Pass-Through Payment(TPT) ](/terms/tpt)
-   [MS-DRG(MS-DRG) ](/terms/ms-drg)
-   [New Technology Add-On Payment(NTAP) ](/terms/ntap)
-   [Inpatient Prospective Payment System(IPPS) ](/terms/ipps)

You may also need

Auto-suggested from Reimbursement and shared keywords.

-   [Site-Neutral Payment ](/terms/site-neutral-payment)
-   [Bundled Payment ](/terms/bundled-payment)
-   [CMS IDE Coverage (Category A & B) ](/terms/ide-coverage)
-   [LCD and NCD ](/terms/lcd-ncd)
-   [ASC Site-of-Service Shift ](/terms/asc-shift)
-   [Budget Impact Model(BIM) ](/terms/budget-impact-model)

[All Reimbursement terms](/terms?cat=Reimbursement)

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